Clinical trials of genome-editing agents — including CRISPR–Cas9 editors, zinc finger nucleases and TALENs — are pushing ex vivo, immuno-oncology and in vivo treatment frontiers.
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As the United States races to ramp up testing for the pandemic coronavirus using technology based on the tried-and-true polymerase chain reaction (PCR), alternative approaches are beginning to roll ...
Biotech start-ups are racing to create faster and more accurate ways to test for coronavirus as countries including the US and the UK struggle to expand production of existing ...
In total, the women profiled in C&EN's 2020 Trailblazers have launched more than 30 start-ups aimed at developing treatments for rare diseases, building better batteries, and more. They’re scientists ...
Who are the greatest scientists of all time? Chances are, Albert Einstein, Isaac Newton or other big names probably come to mind — and for good reason. Those scientists made ...
If your only CRISPR tool is an ordinary Cas9 enzyme, you might imagine that every genome editing problem has the same solution, a blunt double-strand break. Fortunately, ordinary Cas9 ...
Jennifer Doudna will be the first to tell you that she didn’t invent CRISPR, but she did help start the CRISPR revolution. In 2012, she was part of a ...
Jennifer Doudna wears her responsibility lightly. The scientist who co-discovered Crispr does not appear to be weighed down by the burden of her creation: the revolutionary gene-editing technology that ...
CRISPR, the breakthrough method for editing genes, has the potential to improve our lives. But one of its inventors warns us scientists may be tempted to change life itself ...
It started out as “sort of a stupid thing to do”, recalls Joe Bondy-Denomy, a microbiologist at the University of California, San Francisco. As a graduate student in the ...
Two global pioneers of modern gene-editing technology were awarded Monday Israel’s prestigious Wolf Prize in medicine.
The Wolf Foundation said it was recognizing Jennifer Doudna and Emmanuelle Charpentier for their ...
The crystal ball has had its ups and downs as a means of divination. Although it was esteemed by the Druids and other ancient peoples, the crystal ball fell ...
This is a story of another time, of a plausible future 30 years from now, give or take, in which the human experience of life and health (and perhaps ...
The scientist who created the world’s first known genetically modified babies, stunning the global scientific community, has been sentenced by a Chinese court to three years in prison, state media ...
The Chinese researcher who stunned and alarmed the international scientific community with the announcement that he had created the world's first gene-edited babies has been sentenced to three years ...
A Chinese scientist who set off an ethical debate with claims that he had made the world’s first genetically edited babies was sentenced Monday to three years in prison ...
It began as an effort to understand how microbes fight viral infections. Within their chromosomes bacteria store snippets of DNA taken from the viruses they encounter. These fragments, which ...
Will paper money disappear? Will gene-tailored medicine transform how we treat disease? And will you finally trade in that juicy steak for “cell grown” meat?
As a new decade begins, ...
Have you heard the news about sickle cell anaemia and beta thalassemia, the devastating diseases which prevent red blood cells carrying as much oxygen as they should? A new, ...
It was a bustling year for the drug industry, filled with acquisitions, substantial investment in promising technologies, and a steady stream of new drug approvals.
Pharma behemoths merged, forming even ...
Around this time last November, Chinese scientist He Jiankui stunned the world when he revealed the birth of the first known gene-edited babies. Working in relative secrecy, he had ...
Victoria Gray was used to the attacks of excruciating pain. They came regularly, more than a half-dozen times per year, and were a side effect of her sickle cell ...
There are key moments in the history of every disruptive technology that can make or break its public perception and acceptance. For CRISPR-based genome editing, such a moment occurred ...
What differentiates a woman leader in biopharma R&D from a man?
Not much, except there are fewer of them in senior posts. Data suggest women are not more risk-averse, family-oriented ...
The powerful gene-editing technique known as CRISPR has raised a lot of hope in recent years for its potential to offer new ways to treat many diseases, including cancer. But until ...
Ever since the discovery of the structure of DNA in the 1950s, scientists have been dreaming about rewriting the code of life. What if we could correct genetic mutations that ...
As investors await results from the first U.S. clinical trials of the gene-editing system known as Crispr, scientists are focused on finding ways to administer it directly into humans, ...
Denis Rebrikov also told Nature that he does not plan to implant gene-edited embryos until he gets regulatory approval.
Russian biologist Denis Rebrikov has started gene editing in eggs donated by women ...
The first decade of the 21st century introduced us to sweeping mobile and social revolutions largely driven by names like Jobs, Zuckerberg and Bezos. In the second decade that's now ...
Today, the U.S. Patent and Trademark Office (USPTO) granted a new CRISPR-Cas9 patent to the University of California (UC), University of Vienna, and Emmanuelle Charpentier covering new methods of gene editing in prokaryotic ...
The U.S. Patent and Trademark Office (USPTO) today granted the University of California (UC) and its partners, the University of Vienna and Emmanuelle Charpentier, a new CRISPR-Cas9 patent, bringing ...
CRISPR co-inventor Jennifer Doudna discussed the gene-editing technology with Bloomberg's Taylor Riggs on "Bloomberg Technology", explaining how it works, its effect on life sciences and clinical research, its applications, ...
Renowned biochemist and genomics researcher Jennifer Doudna has been selected as the recipient of the 2019 Nierenberg Prize for Science in the Public Interest by Scripps Institution of Oceanography ...
Chinese researchers safely treated a man with leukemia and HIV using gene-edited stem cells, a step forward in a field that was shaken last year when another Chinese scientist ...
Jennifer Doudna, winner of the 2018 Kavli Prize in Nanoscience, talks to Scientific American about what it’s like to work in perhaps the hottest research area in all of biology. She also ...
The U.S. Patent and Trademark Office (USPTO) today (Tuesday, Sept. 3) awarded a new CRISPR-Cas9 patent to the University of California (UC), University of Vienna and Emmanuelle Charpentier, bringing ...
The first “test-tube baby” is now more than 40 years old, and all is well with her. Millions more babies have followed by means of in vitro fertilization, or ...
The University of California, the University of Vienna and Emmanuelle Charpentier received an 11th U.S. patent involving CRISPR-Cas9, further expanding the reach of UC’s patented technology relating to this ...
Structural biologist and biochemist Jennifer Doudna has been honored with the 2019 Welfare Betterment Prize, a relatively new Hong Kong-based prize, for her pioneering discovery of CRISPR-Cas9 gene editing.
“Its ...
It’s going to be illegal in California to sell “gene-therapy kits” unless they carry a warning that says not to use them on yourself.
Just one wrinkle: we’re not sure ...
China has used the genome editor more aggressively, on more species, than any other country.
Early one February morning, researchers harvest six eggs from a female rhesus macaque—one of 4000 ...
On 10 June 2017, a sunny and hot Saturday in Shenzhen, China, two couples came to the Southern University of Science and Technology (SUSTech) to discuss whether they would ...
Early one February morning, researchers harvest six eggs from a female rhesus macaque—one of 4000 monkeys chirping and clucking in a massive outdoor complex of metal cages here at ...
2012, scientists Jennifer Doudna and Emmanuelle Charpentier published a seminal study describing a tool called CRISPR that could be used to make cuts in DNA. Since then, CRISPR research has taken ...
The University of California has received two new patents for use of the revolutionary CRISPR-Cas9 technology, increasing its gene-editing patent portfolio to 10. Five more are expected to be ...
The U.S. Patent and Trademark Office (USPTO) has awarded a new patent to the University of California (UC), University of Vienna, and Dr. Emmanuelle Charpentier covering methods of producing ...
A bipartisan trio of senators on Monday introduced a resolution underscoring their opposition to the experiments last year in China that led to the birth of the world’s first genome-edited ...
Jennifer Doudna talks to Richard Waters, the FT's San Francisco bureau chief, about how she discovered the CRISPR Cas-9 system and how it is transforming the world of gene ...
The simmering battle over who was first to invent breakthrough gene-editing technology has erupted again at the U.S. Patent and Trademark Office.
The Patent Trial and Appeal Board will investigate ...
The dispute over valuable patents to the gene-editing tool CRISPR is back on, and the belligerents are once again the Broad Institute of Cambridge, Massachusetts, and the University of ...
The U.S. patent office has declared an interference between a dozen key patents awarded to the Broad Institute on the genome-editing technology CRISPR and 10 CRISPR patent applications submitted by the ...
The Patent Trial and Appeal Board (PTAB) of the U.S. Patent and Trademark Office (USPTO) has declared an interference between 10 University of California patent applications and multiple previously ...
The first day of summer has arrived, and so has STAT’s annual book list of great reads in health, science, and medicine.
Read on for recommendations from CRISPR pioneer Jennifer ...
Jeff Carroll had been married for six months when he and his wife decided not to have children. Carroll, 25 years old and a former corporal in the US ...
As far as experts are concerned, the technology of gene editing is nowhere near ready to be used to create gene-edited babies. This, of course, is separate from the ...
The drug maker GlaxoSmithKline announced Thursday that it would team up with some of the nation’s most prominent CRISPR researchers to use the gene-editing technology in a search for ...
Pioneers in the field of gene-editing technology will collaborate with one of the world's biggest drugmakers on accelerating the search for new medicines using the promising tool known as ...
GlaxoSmithKline is launching a rare partnership with an American university through which the UK drugmaker will fund more than 20 scientists at a new laboratory focused on human genome ...
When Hal Barron unveiled his grand plan to turn GlaxoSmithKline’s R&D group around, he championed genetics as one of two key focuses for the UK pharma giant, announcing a ...
GlaxoSmithKline is joining forces with the University of California to dig into how gene mutations cause disease and to use CRISPR to discover new drugs. The partners will set up a ...
