Single-Cell RNA Sequencing Provides Insight Into Heart Development in Mice
Researchers have developed a catalog of genes that are expressed during heart development in mice, which they said could be used to better understand how birth defects arise. Birth defects affect about 5 percent of children, and congenital heart malformations are the most common.
Using single-cell RNA sequencing, researchers from the Gladstone Institute of Cardiovascular Disease and elsewhere analyzed nearly 40,000 murine cardiac precursor cells during cardiogenesis.
